Sex differences in response to chronic mild stress and congenital serotonin deficiency

Sex differences in response to chronic mild stress and congenital serotonin deficiency.

Women exhibit a nearly twofold increased risk of developing depression and anxiety disorders when compared to men, a fact that has been hypothesized to result in part from increased stress susceptibility. Here, we used the tryptophan hydroxylase-2 R439H knock-in mouse (Tph2KI) and the chronic unpredictable mild stress (CMS) model to examine sex differences in response to congenital 5-HT deficie...

Aged rats: sex differences and responses to chronic stress.

Cognitive, as well as physiological, sex differences exist in young adult rats under both basal conditions and following chronic stress; however, few studies have examined whether sex differences remain in aged subjects and whether responses to stress are altered. We compared aged male and female Fischer 344 rats (21.5 months at testing) without stress and when given 21 days of restraint for 6 ...

Sex differences in cortisol response to noxious stress.

OBJECTIVES Evidence has accumulated that men and women show different responses to noxious stimuli, with women exhibiting greater sensitivity to pain than men. Data concerning sex differences in cortisol response patterns have revealed inconsistent results so far. The purpose of the present study was to examine sex differences in subjective pain and cortisol response to a noxious stressor. ME...

Sex differences in chronic stress responses and Alzheimer's disease

Evaluation of gender-related differences in response to oxidative stress in toxoplasma gondii positive serum

  Purpose: Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis. It infects up   to one third of the human population. The aim of this study was to evaluate the effects of T.   gondii infection on induction of oxidative stress in serum of infected men and women.   Materials and Methods: This case-control study was carried out on 150 individuals who had   referred to our center ...